Understanding how sensory perception affects social behavior in autism
Official title: Neural Mechanisms Linking Sensory Perception and Social Behavior
Funded at Yale University · NIH-10842404 · Data updated 2026-11-12
This study is looking at how a brain chemical called oxytocin affects the way people with autism experience their senses and interact socially, to better understand the challenges they face.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $406,418 |
| NIH project number | 5R01NS133434-02 |
| Project ID | NIH-10842404 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older diagnosed with autism spectrum disorders.
✕Less likely to help
Patients without a diagnosis of autism spectrum disorders or those under 21 years old may not benefit from this research.
What this research studies
This research investigates the neurobiological mechanisms that connect sensory perception and social behavior in individuals with autism spectrum disorders (ASD). It focuses on the role of oxytocin, a neuropeptide linked to social behaviors, and its impact on sensory processing in the brain. By studying specific neurons in the primary somatosensory cortex, the research aims to uncover how alterations in these mechanisms may contribute to the sensory and social challenges faced by individuals with ASD. The approach includes advanced techniques like electrophysiology to observe neuronal activity and responses.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that improve social functioning and sensory processing in individuals with autism.
How similar studies have gone: Previous research has shown promising results in understanding the role of oxytocin in social behavior, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Che, Alicia Yue — Yale University
- Study coordinator: Che, Alicia Yue
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.