Understanding how reward processing differs in genetic frontotemporal dementia and mood disorders
Reward processing in genetic frontotemporal dementia and mood disorders
This study is looking at how people with genetic frontotemporal dementia and mood disorders experience rewards differently, so we can better understand these conditions and help improve how they are diagnosed.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10543554 on NIH RePORTER |
What this research studies
This research investigates the differences in how individuals with genetic frontotemporal dementia (FTD) and mood disorders process rewards. By examining the earliest behavioral changes in patients with genetic mutations linked to FTD, the study aims to identify distinguishing features between FTD and psychiatric conditions like major depressive disorder and bipolar disorder. The research will involve comparing reward processing in various groups, including presymptomatic genetic FTD patients, their family members, and individuals with mood disorders, to better understand these conditions and improve diagnostic accuracy.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with genetic mutations associated with frontotemporal dementia, as well as those diagnosed with major depressive disorder or bipolar disorder.
Not a fit: Patients without genetic predispositions to frontotemporal dementia or those who do not have mood disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and tailored treatments for patients with frontotemporal dementia and mood disorders.
How similar studies have performed: Previous research has shown promise in understanding the overlap between neurodegenerative diseases and psychiatric disorders, suggesting that this approach could yield valuable insights.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Perry, David C — University of California, San Francisco
- Study coordinator: Perry, David C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.