Understanding how gut bacteria affect peanut allergies in children

Gut Microbiome Dynamics in Peanut Allergy

NIH-funded research Icahn School of Medicine at Mount Sinai · NIH-10452592

This study is looking at how the bacteria in the gut might affect whether kids develop peanut allergies, and it involves collecting stool samples from young children to see how their gut health changes over time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10452592 on NIH RePORTER

What this research studies

This research investigates the role of gut microbiota in the development and resolution of peanut allergies in children. By analyzing stool samples from infants and young children, the study aims to identify specific gut bacteria that may influence the risk of developing peanut allergies. Participants will be monitored over time to observe changes in their gut microbiome and how these changes relate to peanut allergy outcomes. The research utilizes advanced sequencing techniques to profile the gut microbiome and correlate it with allergy development.

Who could benefit from this research

Good fit: Ideal candidates for this research are infants and young children who are at high risk for developing peanut allergies.

Not a fit: Patients who are already diagnosed with peanut allergies or those outside the age range of 0-11 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing or treating peanut allergies in children.

How similar studies have performed: Previous studies have shown promising results in understanding gut microbiota's role in other food allergies, suggesting potential for success in this area as well.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Disease Frequency Surveys
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.