NIH-funded research R01 grant

Understanding how glaucoma affects daily life and quality of life

Official title: Functional Testing and Quality of Life in Glaucoma

Funded at Legacy Emanuel Hospital and Health Center · NIH-11418060 · Data updated 2026-11-12

This project looks at how different patterns of vision loss from glaucoma influence everyday activities and overall well-being, and aims to translate that into practical guidance for patients and clinicians.

More Glaucoma research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionLegacy Emanuel Hospital and Health Center
NIH-funded
Lab location1 site (Portland, UNITED STATES)
Project startSeptember 30, 2023
Project endApril 30, 2027
Funding year2026
Award (this year)$668,852
NIH project number5R01EY034554-04
Project IDNIH-11418060 on NIH RePORTER

Who could benefit from this research

Could help

Adults with glaucoma who experience central or peripheral visual field loss and are navigating daily activities and treatment decisions.

Less likely to help

Patients with glaucoma whose vision loss patterns do not significantly impact daily living or who are not concerned with quality-of-life measures may see limited benefit.

What this research studies

Glaucoma can cause uneven vision loss, and this research will identify which parts of the visual field matter most for quality of life. The team will create simple, real-world metrics that predict how a patient’s vision problems affect daily tasks without relying solely on lengthy questionnaires. These metrics will help clinicians tailor treatment and counseling to each patient’s unique vision loss pattern. The project focuses on patient-reported outcomes and practical activity implications to support better disease management and adherence to treatment.

Why it matters

Potential benefit: Patients could receive personalized guidance on how their specific vision loss may affect daily activities and what management choices might best protect quality of life.

How similar studies have gone: Earlier work shows that vision loss location influences daily function, and this project aims to translate that into actionable patient-facing metrics.

Where this research is happening

  • Legacy Emanuel Hospital and Health Center
    Portland, United States
    Active

Researchers

  • Principal investigator: Gardiner, Stuart — Legacy Emanuel Hospital and Health Center
  • Study coordinator: Gardiner, Stuart

Related research

Other NIH-funded projects on the same topics.

  • IOP and CSF Pressure in Glaucoma Risk

    This grant studies how eye pressure and cerebrospinal fluid pressure together influence glaucoma risk and vision loss.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11644421

  • Comparing tube positions in glaucoma implants to protect corneal cells

    This trial compares two tube placements for glaucoma drainage implants to see which better protects corneal cells and controls eye pressure in people with uncontrolled glaucoma.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11520347

  • Automated topographic test for glaucoma detection and progression

    A new automated method uses topographic structure-function mapping to help diagnose glaucoma earlier and track its progression in patients.

    NIH research Columbia University Health Sciences · New York, United States · NIH-11516608

  • Using AI on eye scans and genes to predict glaucoma risk

    This project uses artificial intelligence on eye scans, vision tests, and genetic information to find people most likely to develop or have worsening glaucoma.

    NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11469603

  • AI-based glaucoma screening in community health centers

    A new, easy-to-use AI screening approach will be tested in federally funded health centers to help identify people at risk for glaucoma, especially in communities with higher risk.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11454104

  • Understanding how glaucoma genes control eye cell function

    A long-term research project will study how genetic factors affect eye cells in adults with glaucoma to uncover new ideas for protecting vision.

    NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-11450761

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.