Understanding how aging affects brain function, walking, and thinking skills

Trajectories and modifiable risk factors of brain, gait, and cognitive decline in aging and pre-dementia

NIH-funded research Albert Einstein College of Medicine · NIH-10808994

This study looks at how getting older affects your brain health, walking, and thinking skills, especially for older adults who might be starting to have some memory issues, to find ways to help improve their quality of life and prevent falls and dementia.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionAlbert Einstein College of Medicine NIH-funded
Lab location1 site (Bronx, United States)
Project IDNIH-10808994 on NIH RePORTER

What this research studies

This research investigates how aging impacts brain health, walking ability, and cognitive function in older adults. It focuses on identifying the changes in brain structure and function that may lead to difficulties in walking and thinking, particularly in those who are beginning to experience cognitive decline. By studying both cognitively healthy older adults and those in early stages of cognitive decline, the research aims to uncover modifiable risk factors that could help improve quality of life and reduce healthcare costs associated with falls and dementia.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults, particularly those who are cognitively healthy or in the early stages of cognitive decline.

Not a fit: Patients who are significantly impaired in their cognitive function or have advanced dementia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to strategies that help maintain mobility and cognitive function in older adults, potentially delaying or preventing dementia.

How similar studies have performed: Previous research has shown promising results in understanding the relationship between gait and cognitive decline, indicating that this approach could yield valuable insights.

Where this research is happening

Bronx, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.