Understanding how aging affects brain function, walking, and thinking skills

Trajectories and modifiable risk factors of brain, gait, and cognitive decline in aging and pre-dementia

['FUNDING_R01'] · ALBERT EINSTEIN COLLEGE OF MEDICINE · NIH-11052249

This study is looking at how getting older affects your brain health, walking, and thinking skills, especially for those who might be starting to have some memory or thinking challenges, to find ways to help improve your quality of life as you age.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorALBERT EINSTEIN COLLEGE OF MEDICINE (nih funded)
Locations1 site (BRONX, UNITED STATES)
Trial IDNIH-11052249 on ClinicalTrials.gov

What this research studies

This research investigates how aging impacts brain health, walking ability, and cognitive function in older adults. It focuses on identifying the changes in brain structure and function that may lead to difficulties in walking and thinking, particularly in those who are starting to experience cognitive decline. By analyzing these changes, the research aims to uncover modifiable risk factors that could help improve the quality of life for older adults. Participants will be monitored over time to track their brain health and walking patterns, providing valuable insights into the aging process.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults, particularly those who are cognitively healthy or in the early stages of cognitive decline.

Not a fit: Patients with advanced dementia or severe mobility impairments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to strategies that help prevent or slow down cognitive decline and improve mobility in older adults.

How similar studies have performed: Previous research has shown promising results in understanding the relationship between gait and cognitive decline, indicating that this approach has potential for success.

Where this research is happening

BRONX, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.