Testosterone Replacement to Reduce Pain for Men with Opioid-Related Low Testosterone

Who could benefit from this research

What this research studies

Many men on long-term opioids have low testosterone, which may worsen pain. The study will examine whether restoring normal testosterone levels can lessen pain and improve quality of life in these patients. Researchers at Brigham and Women’s Hospital will enroll men on opioid therapy and administer testosterone in a carefully monitored way to measure pain, function, and well-being. The goal is to determine if testosterone replacement can break the cycle of higher opioid needs by alleviating pain more effectively.

Why it matters

Where this research is happening

• Brigham and Women's Hospital
  Boston, United States Active

Researchers

• Principal investigator: Basaria, Shehzad — Brigham and Women's Hospital
• Study coordinator: Basaria, Shehzad

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.