The effects of testosterone therapy on bone health in men with diabetes and low testosterone levels
Official title: Testosterone Therapy and Bone Quality in Men with Diabetes and Hypogonadism
Funded at Michael E Debakey VA Medical Center · NIH-10977050 · Data updated 2026-11-12
This study is looking at how testosterone therapy might help improve bone health in men who have diabetes and low testosterone levels, so if you're dealing with these issues, this research could offer some helpful insights into your treatment options.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Michael E Debakey VA Medical Center NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | October 1, 2019 |
| Project end | September 30, 2025 |
| Funding year | 2025 |
| NIH project number | 5I01CX001665-06 |
| Project ID | NIH-10977050 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are men diagnosed with type 2 diabetes and hypogonadism who are experiencing bone health issues.
✕Less likely to help
Patients who do not have diabetes or low testosterone levels may not benefit from this research.
What this research studies
This research investigates how testosterone therapy impacts bone quality in men who have both diabetes and low testosterone levels. It aims to understand the relationship between testosterone, glucose metabolism, and bone health, particularly focusing on how testosterone therapy may influence bone turnover and strength. The study will involve measuring bone density and other markers to assess changes in bone health before and after testosterone treatment. By examining these factors, the research seeks to provide insights into potential treatment options for men facing these health challenges.
Why it matters
Potential benefit: If successful, this research could lead to improved bone health and reduced fracture risk for men with diabetes and low testosterone.
How similar studies have gone: Previous studies have indicated potential benefits of testosterone therapy in similar patient populations, suggesting this approach may be promising.
Where this research is happening
-
Michael E Debakey VA Medical Center
Houston, United States Active
Researchers
- Principal investigator: Villareal, Reina C — Michael E Debakey VA Medical Center
- Study coordinator: Villareal, Reina C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.