NIH-funded research R01 grant

Telemedicine and mobile health support to ease symptoms for advanced cancer patients in rural areas

Official title: Randomized clinical trial of a telemedicine-mHealth symptom cluster intervention for advanced cancer patients: Increasing access in rural communities

Funded at Ohio State University · NIH-11391236 · Data updated 2026-11-12

A short, patient-friendly trial tests a four-module telemedicine-mHealth program designed to help people with advanced cancer who live in rural communities feel better and sleep more soundly.

More Advanced Cancer research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startSeptember 1, 2024
Project endAugust 31, 2029
Funding year2026
Award (this year)$652,743
NIH project number5R01CA281885-03
Project IDNIH-11391236 on NIH RePORTER

Who could benefit from this research

Could help

Adults with advanced cancer living in rural communities who have notable sleep or mood-related symptoms.

Less likely to help

Patients without significant symptom burden or those unable to use mobile/telehealth tools may derive little benefit.

What this research studies

This project builds on a earlier pilot and uses a brief, four-module, at-home program delivered through telemedicine and mobile health tools to help manage sleep problems, worry, depression, and fatigue. It aims to provide practical skill-building that patients can use in daily life, without requiring many in-person visits. Participants will engage with digital modules, track symptoms, and receive guided support to improve quality of life despite advanced cancer. If successful, the program could become a scalable option for rural patients who have limited access to cancer-support resources.

Why it matters

Potential benefit: If successful, patients could experience less sleep disturbance, reduced worry and depression, and improved energy and daily functioning.

How similar studies have gone: Preliminary data from a pilot trial showed meaningful improvements in sleep, worry, depression, and fatigue.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Wells-Di Gregorio, Sharla Maelyn — Ohio State University
  • Study coordinator: Wells-Di Gregorio, Sharla Maelyn

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.