Telehealth and mobile program to ease sleep, worry, depression, and fatigue for people with advanced cancer in rural areas

Randomized clinical trial of a telemedicine-mHealth symptom cluster intervention for advanced cancer patients: Increasing access in underserved rural communities

NIH-funded research Ohio State University · NIH-11180332

A short telehealth and mobile program aims to help people with advanced cancer in rural communities manage sleep problems, worry/anxiety, depression, and fatigue.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project IDNIH-11180332 on NIH RePORTER

What this research studies

If you join, you would be randomly assigned to receive a four-module FOCUS program delivered by telemedicine and mobile tools that blends the most helpful parts of cognitive-behavioral and acceptance-based therapies. The short program teaches practical skills to reduce symptoms when possible and to continue living meaningfully despite symptoms, with a focus on sleep, worry, mood, and fatigue. The researchers will compare symptom, sleep, and quality-of-life outcomes in people with advanced cancer living in underserved rural areas, including Appalachian communities. This larger trial builds on a pilot that showed large improvements and aims to increase access to symptom care where in-person services are limited.

Who could benefit from this research

Good fit: Ideal candidates are adults with advanced cancer who live in underserved or rural areas and are experiencing sleep problems, worry/anxiety, depression, or fatigue and who can use a phone or internet-based app for telehealth.

Not a fit: Patients without these symptoms, those with severe cognitive impairment or communication barriers that prevent using the program, or those with no phone/internet access may not receive benefit from this intervention.

Why it matters

Potential benefit: If successful, this remote program could reduce insomnia, anxiety, depression, and fatigue and improve daily functioning and quality of life for people with advanced cancer in rural areas.

How similar studies have performed: A prior pilot randomized trial of the same four-module FOCUS mHealth program produced large improvements in insomnia, worry, depression, and fatigue, but larger trials are needed to confirm those findings.

Where this research is happening

Columbus, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Advanced Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.