NIH-funded research R01 grant

Meaning-Centered Psychotherapy for Mexican Patients with Advanced Cancer

Official title: Trial of Meaning Centered Psychotherapy for Mexican Patients with Advanced Cancer

Funded at Sloan-Kettering Inst Can Research · NIH-11575359 · Data updated 2026-11-12

A cancer center in Mexico will test a culturally adapted therapy to help Mexican patients with advanced cancer find meaning, peace, and purpose at the end of life.

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Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSloan-Kettering Inst Can Research
NIH-funded
Lab location1 site (New York, United States)
Project startAugust 1, 2024
Project endMay 31, 2029
Funding year2026
Award (this year)$120,960
NIH project number3R01MH137857-03S1
Project IDNIH-11575359 on NIH RePORTER

Who could benefit from this research

Could help

Adults with advanced cancer receiving care at INCan who speak Spanish and are open to psychosocial support.

Less likely to help

Patients who are not interested in psychotherapy or who are too ill to participate may see little or no benefit.

What this research studies

This project adapts Meaning-Centered Psychotherapy for Latinos with advanced cancer and tests it in a large Mexican cancer hospital setting. It builds on prior pilot work in Spanish-speaking populations and brings the intervention to INCan to see if it helps patients cope with mortality, uncertainty, and spiritual concerns. The study will be conducted with patients at the National Mexican Cancer Institute to determine feasibility, acceptability, and potential impact on mood and quality of life. The team will collaborate with Memorial Sloan Kettering in New York to ensure the therapy is culturally relevant and feasible in a high-volume clinical environment.

Why it matters

Potential benefit: If successful, patients may experience improved sense of meaning and reduced distress during advanced cancer.

How similar studies have gone: Preliminary data from a pilot study in Spanish-speaking Latinos suggests feasibility and acceptability, but this will be the first test in Mexican patients.

Where this research is happening

  • Sloan-Kettering Inst Can Research
    New York, United States
    Active

Researchers

  • Principal investigator: Costas-Muniz, Rosario — Sloan-Kettering Inst Can Research
  • Study coordinator: Costas-Muniz, Rosario

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.