Risk factors for shoulder osteoarthritis in adults
Official title: Risk Factors for End-Stage Glenohumeral Osteoarthritis
Funded at Washington University · NIH-11402777 · Data updated 2026-11-12
This project looks at why some people develop painful shoulder osteoarthritis, especially as they age, and how factors like work, sex, and genetics influence the need for shoulder replacement.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 18, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $376,994 |
| NIH project number | 5R01AR083937-03 |
| Project ID | NIH-11402777 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are adults with or at risk for glenohumeral osteoarthritis, including those with prior shoulder issues or relevant occupational exposures.
✕Less likely to help
Individuals without shoulder OA risk factors or related medical data may not directly benefit from this research.
What this research studies
If you have or are at risk for glenohumeral OA, this project will study how modifiable things like occupation and non-modifiable factors such as age, sex, and genetics contribute to the condition. Researchers will use existing medical records and genetic information to identify patterns that may predict who develops OA and who will need shoulder replacement. The study aims to inform better counseling and identify opportunities for earlier evaluation and prevention in high-risk groups. The findings could eventually guide personalized prevention and treatment strategies for patients facing shoulder OA.
Why it matters
Potential benefit: The study could lead to better risk prediction and earlier, more targeted care for people at risk of shoulder OA.
How similar studies have gone: Prior work has identified general OA risk factors, but specific glenohumeral OA risk profiles are still under investigation.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Rowlands, Elizabeth Yanik — Washington University
- Study coordinator: Rowlands, Elizabeth Yanik
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.