Investigating the causes of shoulder arthritis

Risk Factors for End-Stage Glenohumeral Osteoarthritis

NIH-funded research Washington University · NIH-10857493

This study is looking at what might increase the chances of developing shoulder arthritis, especially focusing on things we can change, like job activities, as well as things we can't change, like age and family history, to help find ways to prevent and treat this condition for people who might be at risk.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-10857493 on NIH RePORTER

What this research studies

This research focuses on understanding the risk factors associated with glenohumeral osteoarthritis, a condition that can severely impact shoulder function. By examining both modifiable factors, such as occupation, and non-modifiable factors like age and genetics, the study aims to identify specific risks that lead to this type of arthritis. The research will utilize data from electronic medical records and genetic studies to provide insights that could guide prevention and treatment strategies for patients at risk. Ultimately, this work seeks to improve patient counseling and identify high-risk groups for early evaluation.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals at risk for glenohumeral osteoarthritis, particularly those with a history of shoulder instability or specific occupational exposures.

Not a fit: Patients who do not have risk factors for shoulder arthritis or those with other unrelated shoulder conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better prevention strategies and treatment options for patients suffering from shoulder arthritis.

How similar studies have performed: While there has been significant research on osteoarthritis in other joints, this specific investigation into glenohumeral osteoarthritis is relatively novel and has not been extensively studied.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.