NIH-funded research R01 grant

REVITALIZE: a telehealth program to reduce fatigue interference for adults with advanced ovarian cancer on PARP inhibitors

Official title: Randomized trial of REVITALIZE: A telehealth intervention to reduce fatigue interference among adults with advanced ovarian cancer on PARP inhibitors

Funded at Dana-Farber Cancer Inst · NIH-11370593 · Data updated 2026-11-12

A telehealth program called REVITALIZE aims to help adults with advanced ovarian cancer on PARP inhibitors feel less affected by fatigue and maintain better daily functioning.

More Ovarian Cancer research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDana-Farber Cancer Inst
NIH-funded
Lab location1 site (Boston, United States)
Project startJune 1, 2024
Project endMay 31, 2029
Funding year2026
Award (this year)$677,174
NIH project number5R01CA289547-03
Project IDNIH-11370593 on NIH RePORTER

Who could benefit from this research

Could help

Adults (21+) with advanced ovarian cancer currently taking PARP inhibitors and experiencing fatigue interference.

Less likely to help

Patients not on PARP inhibitors or not experiencing fatigue interference may see limited or no benefit.

What this research studies

This project tests a remote, accessible program designed to lessen how fatigue disrupts daily life for people with advanced ovarian cancer on PARP inhibitors. The approach is built on behavioral strategies delivered through telehealth, tailored to the needs of patients living with ongoing cancer treatment. The study will measure fatigue interference, quality of life, and treatment adherence to see if the program helps patients stay on their prescribed therapy. Given the cancer context, the research focuses on real-world applicability and patient-reported outcomes that matter to daily living. Results could guide future supportive care approaches for similar cancer populations.

Why it matters

Potential benefit: If successful, patients may experience less fatigue-related disruption and better ability to maintain treatment and daily activities.

How similar studies have gone: Preliminary pilots and related fatigue-management work in cancer have shown promising improvements in quality of life and adherence.

Where this research is happening

  • Dana-Farber Cancer Inst
    Boston, United States
    Active

Researchers

  • Principal investigator: Wright, Alexi a — Dana-Farber Cancer Inst
  • Study coordinator: Wright, Alexi a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.