Pulsatility in the Retina and Blood Flow in Glaucoma
Official title: Pulsatility in the Retina in Glaucoma
Funded at Legacy Emanuel Hospital and Health Center · NIH-11432658 · Data updated 2026-11-12
A project to study how pulsation and blood flow in the eye relate to glaucoma, using patient eyes and clinically available imaging tools.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Legacy Emanuel Hospital and Health Center NIH-funded |
| Lab location | 1 site (Portland, UNITED STATES) |
| Project start | September 1, 2026 |
| Project end | April 30, 2030 |
| Funding year | 2026 |
| Award (this year) | $702,487 |
| NIH project number | 1R01EY039375-01 |
| Project ID | NIH-11432658 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with glaucoma or at risk of glaucoma who can undergo retinal imaging and eye examinations.
✕Less likely to help
Some patients may not experience direct benefit if their disease does not involve detectable pulsatility changes.
What this research studies
This project uses eye instruments already approved for clinic visits to map how blood flow and vessel pulsatility change during the heartbeat in people with glaucoma. Researchers will compare pulsatility patterns in eyes with progressing disease to those with stable disease, to understand how eye vessels respond to the pulse. They will create maps of vessel diameter changes and blood flow pulsatility, and test ideas about what causes these patterns. The goal is to identify potential new diagnostic tests that could help tailor care for glaucoma patients. The work combines clinical measurements with analyses that link biomechanics and blood flow to disease progression.
Why it matters
Potential benefit: If successful, patients may gain new diagnostic tools to detect or monitor glaucoma based on pulsatility and blood flow patterns.
How similar studies have gone: Previous work suggests pulsatility differences in eyes with progressing glaucoma, supporting continued investigation.
Where this research is happening
-
Legacy Emanuel Hospital and Health Center
Portland, United States Active
Researchers
- Principal investigator: Gardiner, Stuart — Legacy Emanuel Hospital and Health Center
- Study coordinator: Gardiner, Stuart
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.