PHORA: Better Care for Pulmonary Hypertension with a Smart Decision Tool
Official title: PHORA-Pulmonary Hypertension Outcome Risk Assessment
Funded at Sentara Health · NIH-11417939 · Data updated 2026-11-12
A researchers team is building a patient-focused computer tool to help doctors choose treatments for people with pulmonary hypertension, including children and adults.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sentara Health NIH-funded |
| Lab location | 1 site (Virginia Beach, United States) |
| Project start | January 5, 2024 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $492,961 |
| NIH project number | 5R01HL164906-06 |
| Project ID | NIH-11417939 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include adults and children with pulmonary arterial hypertension who may benefit from data-driven treatment guidance and future registry participation.
✕Less likely to help
Patients outside PAH or without access to centers that implement CDSS tools may not directly benefit.
What this research studies
PHORA, a multi-platform clinical decision support system, will use existing trial data, registries, and biobanks to guide treatment choices in PAH and to improve how new trials are designed. The project brings together engineers, clinicians, data scientists, and patient-care experts to create a tool that clinicians can trust and patients can benefit from. The effort includes co-creating the system with stakeholders and planning a future multi-center registry to keep refining the model. If successful, PHORA could help doctors tailor therapies, potentially improving outcomes and reducing unnecessary treatments.
Why it matters
Potential benefit: If PHORA proves effective, patients with PAH could receive more personalized, faster, and potentially more cost-efficient care.
How similar studies have gone: Previous similar decision-support efforts in other diseases have shown promise, but this project remains exploratory and will require validation.
Where this research is happening
-
Sentara Health
Virginia Beach, United States Active
Researchers
- Principal investigator: Benza, Raymond Louis — Sentara Health
- Study coordinator: Benza, Raymond Louis
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.