Clinical CT Imaging to identify and subtype pulmonary hypertension in COPD
Official title: Clinical CT Imaging for Screening and Subtyping of Pulmonary Hypertension in COPD
Funded at University of California Los Angeles · NIH-11583955 · Data updated 2026-11-12
A new CT imaging approach aims to help doctors detect and classify pulmonary hypertension in people with COPD.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | May 1, 2025 |
| Project end | February 28, 2029 |
| Funding year | 2026 |
| Award (this year) | $628,256 |
| NIH project number | 7R01HL176686-02 |
| Project ID | NIH-11583955 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with COPD who undergo CT imaging and/or have suspected pulmonary hypertension.
✕Less likely to help
Patients without COPD or without suspected pulmonary hypertension may not benefit.
What this research studies
This project will analyze CT scans from COPD patients to understand how lung blood vessels and surrounding tissue change when pulmonary hypertension is present. Using advanced imaging features and from existing NIH datasets, researchers will look for patterns that distinguish PAH-related changes from COPD-related changes. The goal is to improve screening and provide better clues for treatment decisions in a real-world setting. The study leverages multicenter data to explore how CT-derived measurements relate to disease subtypes and patient outcomes.
Why it matters
Potential benefit: If successful, this work could lead to earlier, more accurate detection and better-tailored treatments for COPD patients with pulmonary hypertension.
How similar studies have gone: Previous work has described CT features of pulmonary vascular remodeling in PH, but this project seeks to enhance subtype differentiation in COPD.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Rahaghi, Farbod Nicholas — University of California Los Angeles
- Study coordinator: Rahaghi, Farbod Nicholas
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.