NIH-funded research R01 grant

Peer-led TB-HIV Education and Adherence Support in Uganda

Official title: Peer-led Implementation of TB-HIV Education and Adherence Counseling in Uganda

Funded at Yale University · NIH-11538516 · Data updated 2026-11-12

A group of trained peers helps people with TB and TB-HIV in Uganda stick to treatment and stay informed, with results studied across several clinics in a large, real-world trial.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startSeptember 5, 2024
Project endJune 30, 2029
Funding year2026
Award (this year)$370,557
NIH project number3R01HL176337-03S1
Project IDNIH-11538516 on NIH RePORTER

Who could benefit from this research

Could help

Adults with TB and/or TB-HIV co-infection who receive care in participating Ugandan clinics and are engaged in adherence support.

Less likely to help

Individuals not involved with TB or TB-HIV care in the participating sites may not directly benefit.

What this research studies

This project trains peers with TB to lead education and adherence activities, reorganizes clinic workflows, and uses a structured checklist and personalized plans to improve TB and HIV treatment adherence. It will test these peer-led strategies across 16 sites in Uganda using a cluster-randomized design to measure real-world effectiveness and how well the approach can be implemented at scale. The study combines care improvements with rigorous evaluation to generate evidence that could guide TB-HIV programs in Uganda and beyond, including the United States. The trial is conducted in collaboration with Walimu and Yale University, and it aims to produce practical tools and policies that clinics can adopt to boost treatment completion and outcomes.

Why it matters

Potential benefit: If successful, patients could experience higher treatment completion rates, better TB and HIV outcomes, and more streamlined clinic care.

How similar studies have gone: Previous peer-led strategies in HIV care informed this approach and show promise for improving adherence and education.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Davis, John Lucian — Yale University
  • Study coordinator: Davis, John Lucian

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.