NIH-funded research NIH-funded research

Pediatric Cancer Drug Testing Coordinating Center

Official title: Pediatric Oncology In Vivo Testing Program Coordinating Center

Funded at Jackson Laboratory · NIH-11537642 · Data updated 2026-11-12

A coordinating center is coordinating how young patients’ cancer models are tested with targeted drugs to help improve pediatric cancer outcomes.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJackson Laboratory
NIH-funded
Lab location1 site (Bar Harbor, United States)
Project startAugust 25, 2021
Project endJune 30, 2027
Funding year2026
Award (this year)$403,496
NIH project number3U24CA263963-05S1
Project IDNIH-11537642 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are pediatric patients or pediatric cancer models where research findings could inform future trials or therapies.

Less likely to help

Patients not eligible for pediatric in vivo testing or without pediatric cancer involvement may not directly benefit.

What this research studies

This grant supports a coordinating center that manages in vivo testing of anti-cancer drugs for children, aligning adult and pediatric research to speed translation. It brings together experts in cancer models, data management, informatics, and multi-site collaboration to standardize testing and share results. By coordinating public-private partnerships, the project aims to streamline decision making and ensure timely, consistent testing across sites for pediatric oncology. The center focuses on ensuring safe, effective evaluation of targeted agents in pediatric contexts while meeting updated U.S. requirements.

Why it matters

Potential benefit: If successful, the program could accelerate the availability of effective targeted therapies for children with cancer.

How similar studies have gone: Similar multi-site in vivo testing programs have shown that standardized testing can improve the relevance and speed of translating agents to pediatric trials.

Where this research is happening

  • Jackson Laboratory
    Bar Harbor, United States
    Active

Researchers

  • Principal investigator: Bult, Carol J — Jackson Laboratory
  • Study coordinator: Bult, Carol J

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.