NIH-funded research R01 grant

Mouse Phenome Project: a shared mouse data resource for understanding human disease

Official title: Mouse Phenome Project

Funded at Jackson Laboratory · NIH-11542383 · Data updated 2026-11-12

A large, centralized database of mouse phenotypes is created to help researchers study human diseases by comparing mouse and human biology.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJackson Laboratory
NIH-funded
Lab location1 site (Bar Harbor, United States)
Project startJuly 1, 2004
Project endDecember 31, 2029
Funding year2026
Award (this year)$176,998
NIH project number3R01DA028420-22S1
Project IDNIH-11542383 on NIH RePORTER

Who could benefit from this research

Could help

Not directly a patient-risk study; the work benefits the broader research community and future patient-focused discoveries.

Less likely to help

There is no direct patient participation in this data repository project.

What this research studies

This project builds and maintains an accessible repository of well-documented mouse phenotypes from diverse mouse populations. It focuses on making data easy to search, visualize, and compare so scientists can translate findings into human health insights. The effort includes improving data interoperability and linking mouse data to human genetics to support better use in disease research. Researchers can use the resource to prioritize experiments, analyze patterns, and share results with the broader community.

Why it matters

Potential benefit: If successful, patients could benefit from faster advancement in understanding disease mechanisms and the development of new treatments informed by mouse data.

How similar studies have gone: Similar public data repositories have accelerated disease research by enabling cross-study comparisons and meta-analyses.

Where this research is happening

  • Jackson Laboratory
    Bar Harbor, United States
    Active

Researchers

  • Principal investigator: Chesler, Elissa J — Jackson Laboratory
  • Study coordinator: Chesler, Elissa J

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.