Patient-centered risk profiling to tailor breathlessness care
Official title: Patient-centered risk profiling to improve precision dyspnea management
Funded at University of California Los Angeles · NIH-11445476 · Data updated 2026-11-12
A study from UCLA aims to use AI to identify why a smoker experiences shortness of breath and tailor care to each person.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | August 1, 2026 |
| Project end | July 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $236,250 |
| NIH project number | 1R21HL188677-01 |
| Project ID | NIH-11445476 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults (21 years or older) who have a history of smoking and experience dyspnea and are able to participate in AI-driven assessments.
✕Less likely to help
Individuals without dyspnea or those unwilling to participate in AI-based analyses may derive no direct benefit.
What this research studies
Researchers will collect information from adults who smoke and experience dyspnea to build an AI tool that explains which factors most drive a person’s breathlessness. The project will use explainable AI and Shapley value analysis to show how different factors contribute to each individual’s risk. By clustering patients with similar attribution profiles, the team hopes to identify meaningful subtypes of dyspnea that can guide personalized management. With a clear, patient-friendly output, clinicians could tailor treatments to the driver behind a smoker’s breathlessness.
Why it matters
Potential benefit: If successful, this approach could help clinicians personalize dyspnea treatment for smokers, improving comfort and daily functioning.
How similar studies have gone: Preliminary work in AI-driven phenotyping suggests promise for personalized symptom management, but this exact dyspnea attribution approach is novel.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Shin, Joosun — University of California Los Angeles
- Study coordinator: Shin, Joosun
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.