Personalized oxygen therapies for cancer-related breathing difficulties

Strategies for Personalizing Oxygen and support Therapies for dyspnea in Oncology

NIH-funded research University of Tx Md Anderson Can Ctr · NIH-11074530

This study is looking to help people with advanced cancer who are having trouble breathing by comparing a special program led by respiratory therapists to regular care, to see which one works better at making breathing easier.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Tx Md Anderson Can Ctr NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-11074530 on NIH RePORTER

What this research studies

This research focuses on improving the management of dyspnea, a common and distressing symptom in patients with advanced cancer. It aims to compare a personalized intervention led by respiratory therapists, which includes tailored oxygen and support therapies, against standard care. The study will involve a randomized clinical trial design to assess the effectiveness of these personalized approaches in alleviating breathing difficulties. Patients will receive either the new intervention or enhanced usual care to determine which is more effective in reducing dyspnea.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients with advanced cancer experiencing significant dyspnea.

Not a fit: Patients with early-stage cancer or those not experiencing breathing difficulties may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for managing breathing difficulties in cancer patients, improving their quality of life.

How similar studies have performed: Previous research has indicated limited efficacy of existing palliative interventions for dyspnea, highlighting the need for innovative approaches like this one.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Advanced CancerCancer PatientCancers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.