NIH-funded research R01 grant

Paths to resilience through social networks for older adults with advanced cancer

Official title: Pathways to Resilience of Social Networks of Older Adults with Advanced Cancer

Funded at University of Rochester · NIH-11405491 · Data updated 2026-11-12

This grant looks at how the people and relationships around older adults with advanced cancer help shape their health choices and use of care near the end of life.

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Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Rochester
NIH-funded
Lab location1 site (Rochester, United States)
Project startSeptember 17, 2024
Project endAugust 31, 2029
Funding year2026
Award (this year)$2,250,000
NIH project number4R01CA295130-03
Project IDNIH-11405491 on NIH RePORTER

Who could benefit from this research

Could help

Older adults (65+) with advanced cancer and an estimated survival of less than 12 months, and their key social network members.

Less likely to help

Patients without eligible advanced cancer or those without meaningful social networks may not experience direct benefits.

What this research studies

The project studies how the size, closeness, and support roles of a patient’s social network influence important end-of-life health behaviors. It focuses on adults aged 65 and older with advanced cancer and a limited life expectancy, examining how conversations about illness, advance care planning, and engagement with palliative care are shaped by social ties. Researchers will analyze network structure, the support functions those networks provide, and the quality of relationships to understand their impact on care decisions. The goal is to identify pathways where social connections can promote comfort, alignment with patient preferences, and appropriate use of palliative services. Expect findings that could guide interventions to bolster meaningful discussions and planning with loved ones and care teams.

Why it matters

Potential benefit: If successful, the work could help clinicians and families support timely and patient-centered end-of-life planning for older adults with advanced cancer.

How similar studies have gone: Previous work shows that social networks influence health behaviors, with added value expected from focusing on end-of-life planning.

Where this research is happening

  • University of Rochester
    Rochester, United States
    Active

Researchers

  • Principal investigator: Mohile, Supriya G. — University of Rochester
  • Study coordinator: Mohile, Supriya G.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.