Helping adolescents and young adults with advanced cancer manage stress and build resilience

The Promoting Resilience in Stress Management (PRISM) Intervention: a multi-site randomized controlled trial for Adolescents and Young Adults with advanced cancer

NIH-funded research Dana-Farber Cancer Inst · NIH-10895146

This study is testing a supportive program called PRISM for young people with advanced cancer, which includes personal sessions to help them manage stress and set goals, along with a family meeting to talk about their needs, all aimed at improving their well-being during this tough time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDana-Farber Cancer Inst NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10895146 on NIH RePORTER

What this research studies

This research investigates a program called PRISM, designed to help adolescents and young adults facing advanced cancer. The program consists of four one-on-one sessions that focus on teaching skills such as stress management, mindfulness, and goal-setting, followed by a family meeting to discuss the patient's needs and preferences. By enhancing their ability to cope with the challenges of cancer, the program aims to improve the overall well-being of these young patients. Participants will have the opportunity to express their hopes and concerns, which can lead to better psychosocial outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents and young adults diagnosed with advanced cancer who are seeking support in managing their stress and emotional well-being.

Not a fit: Patients with early-stage cancer or those not experiencing significant stress or psychological distress may not benefit from this intervention.

Why it matters

Potential benefit: If successful, this research could significantly improve the mental health and quality of life for adolescents and young adults with advanced cancer.

How similar studies have performed: Previous pilot studies have shown promising results for similar interventions, indicating that this approach has potential for success.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancersneoplasm/cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.