NIH-funded research R01 grant

Helping adolescents and young adults with advanced cancer manage stress and build resilience

Official title: The Promoting Resilience in Stress Management (PRISM) Intervention: a multi-site randomized controlled trial for Adolescents and Young Adults with advanced cancer

Funded at Dana-Farber Cancer Inst · NIH-10895146 · Data updated 2026-11-12

This study is testing a supportive program called PRISM for young people with advanced cancer, which includes personal sessions to help them manage stress and set goals, along with a family meeting to talk about their needs, all aimed at improving their well-being during this tough time.

More Resilience research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDana-Farber Cancer Inst
NIH-funded
Lab location1 site (Boston, United States)
Project startJuly 29, 2023
Project endJuly 31, 2025
Funding year2023
Award (this year)$351,683
NIH project number7R01CA222486-06
Project IDNIH-10895146 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adolescents and young adults diagnosed with advanced cancer who are seeking support in managing their stress and emotional well-being.

Less likely to help

Patients with early-stage cancer or those not experiencing significant stress or psychological distress may not benefit from this intervention.

What this research studies

This research investigates a program called PRISM, designed to help adolescents and young adults facing advanced cancer. The program consists of four one-on-one sessions that focus on teaching skills such as stress management, mindfulness, and goal-setting, followed by a family meeting to discuss the patient's needs and preferences. By enhancing their ability to cope with the challenges of cancer, the program aims to improve the overall well-being of these young patients. Participants will have the opportunity to express their hopes and concerns, which can lead to better psychosocial outcomes.

Why it matters

Potential benefit: If successful, this research could significantly improve the mental health and quality of life for adolescents and young adults with advanced cancer.

How similar studies have gone: Previous pilot studies have shown promising results for similar interventions, indicating that this approach has potential for success.

Where this research is happening

  • Dana-Farber Cancer Inst
    Boston, United States
    Active

Researchers

  • Principal investigator: Rosenberg, Abby R — Dana-Farber Cancer Inst
  • Study coordinator: Rosenberg, Abby R

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.