NIH-funded research R01 grant

Multisite rollout to help Hispanic kids join cancer trials

Official title: Multisite Implementation of COMPRENDO (ChildhOod Malignancy Peer REsearch NavigatiOn) to improve participation of Hispanic children in cancer clinical trials

Funded at University of California, San Diego · NIH-11374939 · Data updated 2026-11-12

A nationwide study to boost enrollment of Hispanic children with cancer into clinical trials by using trained parent navigators who speak the language and understand health literacy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego
NIH-funded
Lab location1 site (La Jolla, United States)
Project startJuly 26, 2023
Project endJune 30, 2028
Funding year2026
Award (this year)$746,052
NIH project number5R01CA279945-04
Project IDNIH-11374939 on NIH RePORTER

Who could benefit from this research

Could help

Hispanic children (and their guardians) with cancer who are eligible for clinical trials at participating sites.

Less likely to help

Families without access to participating sites or who choose not to enroll in trials may not benefit directly.

What this research studies

This project will build on a proven navigator approach to guide families through the cancer trial process, with culturally and linguistically tailored support. It will test how well trained parent navigators can help families understand trials, meet eligibility, and navigate consent and logistics at multiple sites. The study will focus on reducing barriers to participation and improving timely accrual of Hispanic children into cancer research. Researchers will collect data on participation rates, understanding, and decision-making to identify effective strategies for equitable trial access. Findings could inform standard practices to close disparities in pediatric cancer care.

Why it matters

Potential benefit: If successful, more Hispanic children with cancer could access life-saving trials, potentially improving survival and equity in care.

How similar studies have gone: Preliminary work suggests navigators can improve trial participation, but this multisite test aims to confirm effectiveness across diverse settings.

Where this research is happening

  • University of California, San Diego
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Aristizabal, Paula — University of California, San Diego
  • Study coordinator: Aristizabal, Paula

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.