Mapping microbes and their interactions with host tissues
Official title: Spatially resolved multiomics profiling of microbes and their host tissue
Funded at Yale University · NIH-10932151 · Data updated 2026-11-12
This study is looking at how germs interact with our body, especially when we're taking antibiotics, to help find better ways to treat infections and improve antibiotic use for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 21, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $418,750 |
| NIH project number | 5R35GM150838-02 |
| Project ID | NIH-10932151 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals undergoing antibiotic therapy or those with infections caused by diverse microbial populations.
✕Less likely to help
Patients who are not currently receiving antibiotic treatment or those with non-infectious conditions may not benefit from this research.
What this research studies
This research focuses on understanding how different microbial populations interact with host tissues, particularly during antibiotic treatments. It utilizes advanced techniques to analyze individual microbial cells in their spatial context, which traditional methods cannot achieve. By developing high-resolution spatial omics tools, the research aims to uncover the complexities of microbe-host interactions that are critical for effective treatment strategies. Patients may benefit from insights gained about how to better manage infections and antibiotic therapies.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing infections and antibiotic treatments in patients.
How similar studies have gone: Other research has shown success with similar spatial omics approaches in different fields, indicating potential for breakthroughs in understanding microbial interactions.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Liu, Yang — Yale University
- Study coordinator: Liu, Yang
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.