Lung Transplant Network Data Center coordinating multicenter research
Official title: Lung Transplant Consortium - Data Coordinating Center
Funded at Duke University · NIH-11394228 · Data updated 2026-11-12
A national network is creating a shared data and biosample hub to support a large study of people who receive lung transplants.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | August 5, 2022 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $2,153,303 |
| NIH project number | 5U24HL163122-05 |
| Project ID | NIH-11394228 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults undergoing lung transplantation or related post-transplant follow-up being managed at participating centers.
✕Less likely to help
Patients outside the participating centers or not linked to the transplant process may not directly benefit.
What this research studies
This project will run a centralized Data Coordinating Center to oversee a multi-site registry of lung transplant patients, collecting standardized clinical data and biosamples over several years. It will implement a common protocol across up to 8 clinical centers and 24 sites, with the goal of enrolling about 3,200 lung transplant subjects. The effort leverages Duke University and the University of Pennsylvania to ensure high-quality data collection, biosample handling, and study oversight. The resulting resource will enable future research to improve donor management, candidate selection, and post-transplant care.
Why it matters
Potential benefit: If successful, patients could benefit from better donor matching, improved care pathways, and insights that reduce complications after transplant.
How similar studies have gone: Multicenter transplant studies with centralized data centers have produced robust, generalizable findings in the past.
Where this research is happening
-
Duke University
Durham, United States Active
Researchers
- Principal investigator: Palmer, Scott M — Duke University
- Study coordinator: Palmer, Scott M
Related research
Other NIH-funded projects on the same topics.
-
Exercise-based frailty program for people awaiting lung transplants
A tailored exercise and lifestyle program is being tested to reduce frailty and improve outcomes for people waiting for a lung transplant.
-
Understanding why a lung transplant sometimes fails early and how to tailor treatment
A study of people receiving lung transplants to find molecular differences that cause early graft failure and point to better, personalized therapies.
-
Targeting inflammation and alloimmunity in lung transplant recipients with clazakizumab
A study to see if blocking IL-6 with clazakizumab can improve survival and reduce rejection in people who have received a lung transplant.
-
Vaccination responses in lung transplant patients
This grant studies how people who have received lung transplants respond to COVID-19 vaccines and why their antibody responses may be limited.
-
The Post-Lung Transplant Aging in Immune Cells in Donor Lungs
This grant explores how aging donor lungs affect lung transplant outcomes by studying immune cells called alveolar macrophages.
-
Predictors of Lung Transplant Success and Costs
This study looks at what pre-transplant patient factors and biology predict a smooth recovery and lower costs after lung transplant.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.