Protecting against disability in early Multiple Sclerosis
Reserve against Disability in Early Multiple Sclerosis (RADIEMS) Longitudinal Cohort Study
['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11158621
This project explores how diet and body weight might help people with early multiple sclerosis maintain their brain function and reduce disability over time.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11158621 on ClinicalTrials.gov |
What this research studies
Multiple sclerosis (MS) often leads to problems with thinking and movement due to changes in the brain. This long-term project continues to follow people who were diagnosed with MS early in their disease. We are looking at how lifestyle factors, specifically a healthy diet (like the MIND diet) and maintaining a healthy body weight (BMI), might help preserve brain tissue and overall function. The goal is to understand if these factors can either prevent brain loss or help individuals maintain their abilities even if some brain changes occur. Participants undergo regular MRI scans and comprehensive tests of their thinking and movement skills over several years.
Who could benefit from this research
Good fit: Ideal candidates are individuals diagnosed with multiple sclerosis early in their disease course, especially those who were part of the original RADIEMS cohort.
Not a fit: Patients with advanced multiple sclerosis or those not able to make lifestyle changes may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this research could identify practical lifestyle changes that help people with early MS maintain their brain health and functional abilities for longer.
How similar studies have performed: This project is a renewal of an existing cohort study, building upon prior work to better understand functional decline in multiple sclerosis.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SUMOWSKI, JAMES FRANCIS — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: SUMOWSKI, JAMES FRANCIS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.