NIH-funded research R01 grant

Long-term Effects of a Natural Disaster on Cognitive Aging and Dementia in Older Adults

Official title: Long-term Effects of a Natural Disaster on Cognitive Aging, Dementia, Health and Well-being of Older Adults

Funded at Univ of North Carolina Chapel Hill · NIH-11541242 · Data updated 2026-11-12

This project follows older adults affected by a major natural disaster to understand how long-term stress may influence aging, memory, and risk for dementia.

More Aging research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startSeptember 15, 2020
Project endMay 31, 2031
Funding year2026
Award (this year)$398,147
NIH project number3R01AG065395-06S1
Project IDNIH-11541242 on NIH RePORTER

Who could benefit from this research

Could help

Older adults who were exposed to the 2004 Indian Ocean tsunami and are part of the STAR data framework or similar longitudinal cohorts.

Less likely to help

Individuals without disaster exposure or outside the study cohorts may not directly benefit from this research.

What this research studies

The study uses data from a long-running cohort to track health, thinking skills, and well-being in older adults more than 20 years after a large tsunami. It combines pre-disaster information with multiple follow-ups to identify how exposure to disaster-related stress relates to cognitive decline and Alzheimer’s risk. Researchers will use innovative memory and executive function tasks, plus health markers, to map trajectories over time. The goal is to generate generalizable evidence that can guide prevention and care for aging populations after disasters.

Why it matters

Potential benefit: If successful, it could inform interventions to protect cognition and overall health in older adults after disasters.

How similar studies have gone: Prior long-term observational studies have shown links between stress and cognitive aging, supporting the relevance of this approach.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Frankenberg, Elizabeth a — Univ of North Carolina Chapel Hill
  • Study coordinator: Frankenberg, Elizabeth a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.