NIH-funded research P01 program project

Health, Aging and Dementia in South Africa: A Longitudinal Study

Official title: Health, Aging and Dementia in South Africa: A Longitudinal Study (HAALSI)

Funded at Harvard University D/b/a Harvard School of Public Health · NIH-11536336 · Data updated 2026-11-12

A long-term study in South Africa follows adults as they age to understand how dementia and Alzheimer’s affect people in LMIC settings.

More Aging research and trials

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionHarvard University D/b/a Harvard School of Public Health
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 15, 2013
Project endMay 31, 2028
Funding year2026
Award (this year)$6,385
NIH project number3P01AG041710-12S2
Project IDNIH-11536336 on NIH RePORTER

Who could benefit from this research

Could help

Adults in South Africa, aged 40 and older, who are enrolled or willing to join the longitudinal HAALSI cohort.

Less likely to help

If you are under 40 or not living in the HAALSI study regions, you would not directly benefit.

What this research studies

This program tracks adults in South Africa over many years, collecting surveys, cognitive tests, biomarkers, and death data to understand what puts people at risk for aging-related brain diseases. It builds on previous waves of data and adds new measurements to better connect chronic diseases, aging, and dementia in a low- to middle-income country context. Researchers at Harvard School of Public Health partner with local communities to keep participants engaged and to learn how dementia develops over time in this population.

Why it matters

Potential benefit: The study could inform better prevention and care for dementia in Africa and similar settings.

How similar studies have gone: The HAALSI program has successfully collected multiple waves of data, showing feasibility of long-term cognitive and biomarker assessments in this population.

Where this research is happening

  • Harvard University D/b/a Harvard School of Public Health
    Boston, United States
    Active

Researchers

  • Principal investigator: Berkman, Lisa F — Harvard University D/b/a Harvard School of Public Health
  • Study coordinator: Berkman, Lisa F

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.