NIH-funded research R01 grant

Long-term effects of a natural disaster on aging, cognition, and well-being in older adults

Official title: Long-term Effects of a Natural Disaster on Cognitive Aging, Dementia, Health and Well-being of Older Adults

Funded at Univ of North Carolina Chapel Hill · NIH-11301490 · Data updated 2026-11-12

This project follows older adults affected by a large tsunami to understand how disaster stress might influence memory, thinking skills, health, and well-being many years later.

More Aging research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startSeptember 15, 2020
Project endMay 31, 2031
Funding year2026
Award (this year)$135,013
NIH project number2R01AG065395-06
Project IDNIH-11301490 on NIH RePORTER

Who could benefit from this research

Could help

Older adults who were affected by the 2004 Indian Ocean tsunami and who contributed to the STAR cohort, with available long-term follow-up data.

Less likely to help

Individuals without exposure to the disaster or without long-term follow-up data may have little relevance to this specific study question.

What this research studies

Researchers will use long-term data from a population-representative group, including pre-disaster baselines and 7 post-disaster follow-ups plus more than 20 years of follow-up, to examine how exposure to a major natural disaster affects cognition and related health in older adults. The study focuses on memory and executive function, as well as biological markers of stress and cardiometabolic risk, to trace how the impacts evolve over time. By leveraging existing data from the STAR study in Aceh and North Sumatra, the project aims to generate generalizable evidence about long-term cognitive outcomes after a disaster and the potential links to Alzheimer’s-related dementias. The findings could inform interventions and policies to support aging populations in disaster-prone regions.

Why it matters

Potential benefit: If successful, this research could guide strategies to protect cognitive health and overall well-being of older adults after disasters.

How similar studies have gone: Previous work with disaster cohorts has shown links between stress and cognitive health, but this project will provide long-term, population-level insights over more than two decades.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Frankenberg, Elizabeth a — Univ of North Carolina Chapel Hill
  • Study coordinator: Frankenberg, Elizabeth a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.