NIH-funded research R01 grant

Iodized salt and early brain development in babies of pregnant and breastfeeding women in rural Ethiopia

Official title: Effect of iodized salt in pregnancy and lactation on infant neurodevelopment in rural Ethiopia

Funded at Brigham and Women's Hospital · NIH-11474405 · Data updated 2026-11-12

This grant tests whether giving iodized salt to pregnant and breastfeeding women helps their babies’ brain development.

More Pregnancy research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startJuly 1, 2022
Project endJune 30, 2027
Funding year2026
Award (this year)$175,444
NIH project number3R01HD107475-05S1
Project IDNIH-11474405 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are pregnant women in their first or early second trimester and their infants, particularly in settings with limited access to iodized salt.

Less likely to help

Pregnant or lactating women with access to adequate iodine may see limited or no additional benefit.

What this research studies

The project follows mothers in pregnancy and during the early months after birth to see if iodized salt affects infant brain function. Researchers will use brain measures from babies, gathered through noninvasive EEG tests, to look for changes in neural development. The study builds on an existing randomized trial and compares outcomes with and without iodized salt supplementation during pregnancy and lactation. Results could inform guidelines on iodine nutrition for mothers and young children.

Why it matters

Potential benefit: If successful, the findings could improve infant brain development and help shape public health recommendations on iodine nutrition for pregnant and lactating women.

How similar studies have gone: Previous studies suggest iodine affects brain development, though results have been mixed, making this trial important for clear guidance.

Where this research is happening

  • Brigham and Women's Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Cherkerzian, Sara — Brigham and Women's Hospital
  • Study coordinator: Cherkerzian, Sara

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.