Pregnancy RSV vaccine effects on newborns, breastfeeding, and child health
Official title: Neonatal, Lactation, and Child Health Outcomes Following RSV Vaccination During Pregnancy
Funded at Healthpartners Institute · NIH-11311951 · Data updated 2026-11-12
This project looks at whether getting the RSV vaccine during pregnancy affects newborn health, breastfeeding, growth, development, and allergic outcomes in early childhood.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Healthpartners Institute NIH-funded |
| Lab location | 1 site (Bloomington, UNITED STATES) |
| Project start | August 9, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $673,986 |
| NIH project number | 5R01HD115580-03 |
| Project ID | NIH-11311951 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal participants are pregnant people who received (or plan to receive) the prenatal RSVpreF vaccine and their newborns and young children, particularly those receiving care at participating HealthPartners clinics.
✕Less likely to help
People who are not pregnant, not planning pregnancy, or who did not receive the prenatal RSV vaccine are unlikely to gain direct benefit from participating.
What this research studies
If you join, researchers will follow babies whose mothers got the prenatal RSVpreF vaccine and compare them with babies whose mothers did not get the vaccine. They will use medical records, brief surveys, and routine pediatric visit data to track newborn outcomes, breastfeeding experiences, growth, neurodevelopment, and allergic conditions over time. The team will pay special attention to preterm birth and early neonatal health because the original vaccine trial had limited data for people at high risk of early delivery. Participation may involve allowing access to your and your child’s health records and answering short questionnaires at intervals.
Why it matters
Potential benefit: If successful, this research could provide clearer safety information to help parents and clinicians make informed decisions about RSV vaccination during pregnancy.
How similar studies have gone: A large clinical trial showed the vaccine cuts severe RSV illness in infants, but that trial excluded people at high risk for preterm birth and left unanswered questions about neonatal, lactation, and longer-term child outcomes.
Where this research is happening
-
Healthpartners Institute
Bloomington, United States Active
Researchers
- Principal investigator: Palmsten, Kristin — Healthpartners Institute
- Study coordinator: Palmsten, Kristin
Related research
Other NIH-funded projects on the same topics.
-
Investigating the effects of RSV vaccination during pregnancy on infant health outcomes
This study is looking at how getting the RSV vaccine while pregnant can help keep newborns and young kids healthy, especially for moms at higher risk of having preterm babies, and it aims to reassure pregnant women about the vaccine's safety and benefits for their little ones.
-
Iodized salt and early brain development in babies of pregnant and breastfeeding women in rural Ethiopia
This grant tests whether giving iodized salt to pregnant and breastfeeding women helps their babies’ brain development.
-
IMPILO: New 6-month RR-TB regimen in pregnant and breastfeeding women
A study in pregnant and postpartum women with rifampicin-resistant TB will track how well a new all-oral 6-month treatment works and how well people stick to it.
-
Effects of iodized salt during pregnancy and breastfeeding on infant brain development in rural Ethiopia
Pregnant and breastfeeding people in rural Ethiopia will receive iodized salt to see how it affects their baby’s brain development.
-
Iodized salt for pregnant and breastfeeding mothers to support babies' brain development in rural Ethiopia
This project gives iodized salt to pregnant and breastfeeding women in rural Ethiopia to see if it helps their babies' early brain, attention, and motor development.
-
Effects of restricting non-nutritive sweeteners during pregnancy on infant growth
A study will test whether limiting non-nutritive sweeteners in pregnant and breastfeeding mothers affects how babies eat, grow, and develop in the first two years.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.