NIH-funded research R01 grant

Effects of restricting non-nutritive sweeteners during pregnancy on infant growth

Official title: Effects of a non-nutritive sweetener restriction intervention during pregnancy and lactation on eating behavior, dietary intake, and growth from birth to 24 months

Funded at George Washington University · NIH-11339715 · Data updated 2026-11-12

A study will test whether limiting non-nutritive sweeteners in pregnant and breastfeeding mothers affects how babies eat, grow, and develop in the first two years.

More Pregnancy research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGeorge Washington University
NIH-funded
Lab location1 site (Washington, United States)
Project startSeptember 15, 2026
Project endMay 31, 2031
Funding year2026
Award (this year)$704,708
NIH project number1R01HD121599-01
Project IDNIH-11339715 on NIH RePORTER

Who could benefit from this research

Could help

Pregnant or lactating individuals who use or are considering non-nutritive sweeteners and want to understand potential impacts on their child’s growth.

Less likely to help

Families not consuming or considering non-nutritive sweeteners may not experience a direct change from this study.

What this research studies

The study follows pregnant people and their babies to see if reducing non-nutritive sweeteners during pregnancy and lactation changes infants’ eating behaviors, sugar intake, and growth patterns from birth to 24 months. Researchers will monitor dietary intake, weight trajectories, and developmental markers, using a combination of surveys, infant measurements, and health records. The goal is to understand if maternal NNS exposure influences early eating habits and obesity risk in children.

Why it matters

Potential benefit: If successful, this research could inform dietary guidelines for pregnant and nursing parents to support healthier infant growth.

How similar studies have gone: Previous work has linked maternal NNS exposure to infant outcomes, but experimental human data are limited, making this a novel test of causality.

Where this research is happening

  • George Washington University
    Washington, United States
    Active

Researchers

  • Principal investigator: Smith, Emily R — George Washington University
  • Study coordinator: Smith, Emily R

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.