Investigating how biomolecular condensates function in cells
Official title: Spatially Resolved Molecular Measurement of Biomolecular Condensates
Funded at Ut Southwestern Medical Center · NIH-11065529 · Data updated 2026-11-12
This study is looking at special structures in our cells that help organize important molecules, and by using a new technology, researchers want to see how these structures change in health and disease, which could lead to better treatments for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | April 3, 2024 |
| Project end | January 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $405,331 |
| NIH project number | 5R01HG013358-02 |
| Project ID | NIH-11065529 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing age-related conditions or diseases that may involve cellular dysfunction.
✕Less likely to help
Patients with acute conditions unrelated to cellular aging or dysfunction may not benefit from this research.
What this research studies
This research focuses on biomolecular condensates, which are unique cellular structures that help organize molecules and reactions within cells. By developing a new spatial genomics platform, the research aims to analyze these condensates at a very detailed level, allowing scientists to observe how their molecular content changes in health and disease. This approach will provide insights into the roles of these condensates in various cellular processes, potentially leading to new understandings of cell function and pathology. Patients may benefit from advancements in treatments that target these cellular mechanisms.
Why it matters
Potential benefit: If successful, this research could lead to new insights into cellular processes that may improve treatment strategies for age-related and other diseases.
How similar studies have gone: Other research has shown promising results in understanding cellular processes through similar approaches, indicating potential for success in this novel investigation.
Where this research is happening
-
Ut Southwestern Medical Center
Dallas, United States Active
Researchers
- Principal investigator: Chen, Haiqi — Ut Southwestern Medical Center
- Study coordinator: Chen, Haiqi
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.