Multi-center study on how ventilation during CPR relates to cardiac arrest outcomes
Official title: Multi-center observational study of the association between ventilation and cardiac arrest outcome
Funded at Ut Southwestern Medical Center · NIH-11630823 · Data updated 2026-11-12
A large, real-world study will look at how ventilation during CPR affects survival after out-of-hospital cardiac arrest in adults.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | September 16, 2025 |
| Project end | July 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $181,399 |
| NIH project number | 3R01HL173101-02S1 |
| Project ID | NIH-11630823 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults 21 years or older who have experienced out-of-hospital cardiac arrest and received CPR.
✕Less likely to help
Patients not experiencing OHCA or those outside the 21+ age range would not directly benefit.
What this research studies
This project uses data from multiple centers to analyze ventilation during CPR with a new machine-learning tool that measures ventilation from defibrillator pads. It builds on prior work showing that chest compressions are not always paired with adequate ventilation during standard CPR, and it aims to see how ventilation metrics relate to outcomes in OHCA. Researchers will analyze how different ventilation patterns during continuous chest compressions correlate with survival and brain/organ function after arrest. The study design focuses on leveraging existing OHCA trial data to refine future CPR strategies.
Why it matters
Potential benefit: If successful, findings could inform CPR guidelines to improve survival and neurological outcomes after cardiac arrest.
How similar studies have gone: Previous work showed ventilation during CPR is often suboptimal; this study adds a validated, automated measurement approach to better understand its impact.
Where this research is happening
-
Ut Southwestern Medical Center
Dallas, United States Active
Researchers
- Principal investigator: Idris, Ahamed H — Ut Southwestern Medical Center
- Study coordinator: Idris, Ahamed H
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.