Integrating clinical pharmacists into HIV care to reduce cardiovascular disease in people with HIV
Official title: INTEGRATE RX: Integrating Clinical Pharmacists in HIV care to Mitigate Last-Mile Challenges and Reduce Cardiovascular Disease Burden
Funded at Temple Univ of the Commonwealth · NIH-11551581 · Data updated 2026-11-12
A pharmacist-led program in HIV care aims to prevent and manage heart disease risks like high blood pressure, diabetes, and high cholesterol in people living with HIV.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Temple Univ of the Commonwealth NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | August 25, 2025 |
| Project end | July 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $304,132 |
| NIH project number | 3R01HL179904-02S1 |
| Project ID | NIH-11551581 on NIH RePORTER |
Who could benefit from this research
✓Could help
People living with HIV who are at risk for cardiovascular disease or have existing CVD risk factors and are engaged in HIV care.
✕Less likely to help
Patients not living with HIV or those without cardiovascular risk factors may see limited direct benefit.
What this research studies
This project tests a pharmacist-led approach that integrates cardiovascular disease management into HIV care. It uses a multi-component strategy, including initiation and maintenance of CVD medications, ensuring access to essential medicines, and coordinating peer support for delivery and counseling. The study will design, refine, and evaluate how this integrated care model works in real-world HIV clinics and whether it is cost-effective. The goal is to improve heart health outcomes while maintaining HIV control and patient retention in care.
Why it matters
Potential benefit: If successful, patients with HIV could experience better blood pressure, diabetes, and cholesterol control, potentially lowering heart disease risk.
How similar studies have gone: Prior pharmacist-led interventions in HIV care have improved adherence and clinical outcomes, but this specific integrated CVD approach in HIV care is being tested.
Where this research is happening
-
Temple Univ of the Commonwealth
Philadelphia, United States Active
Researchers
- Principal investigator: Tran, Dan Nguyen Khanh — Temple Univ of the Commonwealth
- Study coordinator: Tran, Dan Nguyen Khanh
Related research
Other NIH-funded projects on the same topics.
-
Understanding how genetic changes in blood cells relate to heart disease in people with HIV
A study will look at how age-related blood cell mutations and large chromosomal changes might contribute to heart disease risk in people living with HIV.
-
Food allergy antibodies linked to heart disease risk in adults
Many adults have antibodies to foods without symptoms, and this study asks whether those antibodies are linked to higher risk of heart disease and related conditions.
-
Mindfulness training to lower cardiovascular risk for moms and babies during pregnancy
A mindfulness program is being tested during pregnancy to help prevent high blood pressure and heart problems for mothers and their babies.
-
Integrating heart care into HIV services in Botswana using statins
This project tests a simple, scalable approach to help people with HIV in Botswana start and stay on statin therapy to prevent heart attacks and strokes.
-
A heart-healthy program for aging HIV patients using therapy pets to help blood pressure
A study tests whether using the human-animal bond from dog ownership can help older adults living with HIV control their blood pressure and improve heart health.
-
Decoding regulatory variants linked to heart disease
A scientist team will study how non-coding genetic changes in heart cells influence cardiovascular disease risk.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.