NIH-funded research R01 grant

Indoor air quality and heart health in COPD patients

Official title: CLEAN AIR Heart 2: Targeting Indoor Air Quality to Improve Cardiovascular Health in COPD

Funded at Johns Hopkins University · NIH-11277069 · Data updated 2026-11-12

A Johns Hopkins-led study will test whether improving indoor air quality helps reduce heart-related problems for people living with COPD.

More COPD research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University
NIH-funded
Lab location1 site (Baltimore, United States)
Project startJuly 15, 2026
Project endApril 30, 2031
Funding year2026
Award (this year)$783,962
NIH project number1R01HL183649-01
Project IDNIH-11277069 on NIH RePORTER

Who could benefit from this research

Could help

Adults with COPD who spend most of their time indoors and are willing to participate in long-term monitoring.

Less likely to help

Individuals without COPD or those who do not spend significant time indoors may not benefit from this study.

What this research studies

This project focuses on adults with COPD who spend most of their time indoors. Researchers will examine how reducing indoor air pollution, including ultrafine particles, affects cardiovascular health and related biological markers. The study plans to use wearable accelerometers and other measurements to track activity, air exposure, and heart-related outcomes in a real-world setting across the United States. Results could guide practical ways to improve home environments to protect heart health in COPD patients.

Why it matters

Potential benefit: If successful, the study could lead to simple, real-world steps to lower cardiovascular risk for people with COPD by improving indoor air.

How similar studies have gone: Previous work suggests indoor air quality affects cardiovascular health, but comprehensive, nationwide intervention data in COPD is still needed.

Where this research is happening

  • Johns Hopkins University
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Raju, Sarath — Johns Hopkins University
  • Study coordinator: Raju, Sarath

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.