Improving treatment for aggressive brain cancer using innovative cell delivery methods
Enhanced Delivery of Cytotoxic Neural Stem Cells for Treatment of Glioblastoma Multiforme Using an Innovative In-situ Thermogelling Hydrogel and Focused Ultrasound
This study is testing a new way to treat glioblastoma, a tough brain cancer, by using a special gel and sound waves to help deliver helpful stem cells directly to the tumor, which could lead to better results and fewer surgeries for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10981700 on NIH RePORTER |
What this research studies
This research focuses on developing a new treatment for glioblastoma multiforme, a highly aggressive brain cancer. It aims to enhance the delivery of induced neural stem cells (iNSCs) to tumors using a novel biodegradable hydrogel and focused ultrasound technology. This approach seeks to provide a long-lasting and non-invasive method for administering these cells, potentially improving their effectiveness in targeting and killing cancer cells. Patients may benefit from a more effective treatment option that reduces the need for repeated surgeries.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with glioblastoma multiforme who are seeking innovative treatment options.
Not a fit: Patients with other types of brain tumors or those who are not eligible for stem cell therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a more effective and less invasive treatment option for patients with glioblastoma multiforme.
How similar studies have performed: Other research has shown promise in using neural stem cells for brain cancer treatment, but this specific approach utilizing a biodegradable hydrogel and focused ultrasound is relatively novel.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Benhabbour, Soumya Rahima — Univ of North Carolina Chapel Hill
- Study coordinator: Benhabbour, Soumya Rahima
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.