Improving heart valve disease assessment using advanced MRI techniques
Official title: A comprehensive valvular heart disease assessment with stress cardiac MRI
Funded at Ohio State University · NIH-10877038 · Data updated 2026-11-12
This study is testing a new type of heart scan to help doctors better understand and treat mitral valve regurgitation, so if you have this condition, it could lead to more accurate diagnoses and better treatment options for you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | August 1, 2021 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $683,214 |
| NIH project number | 5R01HL151697-04 |
| Project ID | NIH-10877038 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with mitral valve regurgitation who require assessment for treatment options.
✕Less likely to help
Patients with other types of heart valve diseases or those who do not have mitral valve regurgitation may not benefit from this research.
What this research studies
This research focuses on enhancing the diagnosis and management of mitral valve regurgitation (MR) through a new stress cardiac MRI protocol. By utilizing advanced cardiovascular MRI techniques, the study aims to provide a more accurate and comprehensive evaluation of MR, which is crucial for determining the best treatment options for patients. The approach seeks to overcome the limitations of traditional echocardiographic methods, offering better predictive power for clinical outcomes. Patients will undergo stress MRI scans to assess their heart function and valve performance more effectively.
Why it matters
Potential benefit: If successful, this research could lead to more precise treatment plans for patients with mitral valve regurgitation, potentially improving their health outcomes.
How similar studies have gone: Previous research has shown that advanced MRI techniques can provide significant improvements in cardiac assessments, suggesting a promising potential for this approach.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Ahmad, Rizwan — Ohio State University
- Study coordinator: Ahmad, Rizwan
Related research
Other NIH-funded projects on the same topics.
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Understanding how blood vessel cells change to help or worsen heart valves
Researchers are studying how endothelial cells change and contribute to mitral valve prolapse to find better ways to treat this common heart valve condition.
-
AI to find early mitral valve problems and predict future heart risks
This project uses artificial intelligence on heart ultrasound images to find early mitral valve changes and predict which adults might later develop serious heart complications.
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Improving heart valve disease diagnosis with stress cardiac MRI
This project aims to create a better way to understand mitral valve problems using a special heart MRI scan, helping doctors decide the best treatment for patients.
-
Understanding the role of PKD3 in heart valve disease
This study is looking into how certain heart cells change and affect heart valve health in people with valvular heart disease, with the hope of finding new ways to treat this condition and help patients feel better.
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Using AI to improve diagnosis and outcomes for mitral valve disease
This study is looking at how we can use advanced computer technology to better understand mitral valve disease, helping doctors spot early signs of problems in heart images so they can provide better care and treatment for patients like you.
-
Understanding Cilia's Role in Heart Valve Disease
This project explores how tiny structures called cilia and certain gene changes might cause common heart valve problems like mitral valve prolapse.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.