Improving heart valve disease diagnosis with stress cardiac MRI

A comprehensive valvular heart disease assessment with stress cardiac MRI

NIH-funded research Ohio State University · NIH-11138573

This project aims to create a better way to understand mitral valve problems using a special heart MRI scan, helping doctors decide the best treatment for patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project IDNIH-11138573 on NIH RePORTER

What this research studies

Many people experience mitral valve regurgitation, a condition where a heart valve doesn't close properly. Currently, diagnosing and deciding when to treat this condition can be challenging with standard tests. Our goal is to develop a new, comprehensive stress cardiac MRI scan that can provide clearer, more detailed information about your heart valve. This advanced imaging could help doctors make more confident decisions about the best time for surgery or other treatments, leading to better outcomes for you.

Who could benefit from this research

Good fit: Patients with mitral valve regurgitation who are seeking a more precise understanding of their condition and treatment options would be ideal candidates.

Not a fit: Patients without mitral valve regurgitation or those not requiring advanced imaging for their heart condition would likely not benefit from this specific research.

Why it matters

Potential benefit: If successful, this new MRI method could lead to more accurate diagnoses and more timely, effective treatment plans for individuals with mitral valve regurgitation.

How similar studies have performed: While cardiovascular MRI has shown promise in predicting outcomes for mitral valve patients, this project focuses on developing and validating a novel stress protocol to overcome existing limitations in routine clinical care.

Where this research is happening

Columbus, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.