NIH-funded research R01 grant

Improving fairness in AI algorithms for glaucoma treatment

Official title: Improving Fairness and Reducing Bias in Artificial Intelligence Algorithms for Glaucoma

Funded at Stanford University · NIH-11030044 · Data updated 2026-11-12

This study is working on smart computer programs that can help doctors predict which glaucoma patients might be at risk of losing their vision, especially focusing on making sure everyone gets fair treatment, no matter their background.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionStanford University
NIH-funded
Lab location1 site (Stanford, United States)
Project startJanuary 1, 2025
Project endDecember 31, 2029
Funding year2025
Award (this year)$654,455
NIH project number1R01EY036893-01
Project IDNIH-11030044 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include glaucoma patients, particularly those from Black and Hispanic communities who are at higher risk for disease progression.

Less likely to help

Patients with early-stage glaucoma or those who do not belong to marginalized communities may not receive direct benefits from this research.

What this research studies

This research focuses on developing personalized prediction algorithms to better understand and manage glaucoma, a leading cause of irreversible blindness. By utilizing artificial intelligence techniques on electronic health records, the study aims to create high-performance predictive models that can identify patients at high risk for vision loss. A key aspect of this research is addressing algorithmic bias, particularly how it affects marginalized groups, to ensure equitable healthcare outcomes. The project will leverage data from the multicenter Sight Outcomes Research Collaborative to evaluate the fairness and effectiveness of these AI algorithms.

Why it matters

Potential benefit: If successful, this research could lead to more accurate predictions and personalized treatment plans for glaucoma patients, ultimately reducing the risk of vision loss.

How similar studies have gone: Previous research has shown success in using AI for predictive modeling in healthcare, but addressing algorithmic bias in this context is a relatively novel approach.

Where this research is happening

  • Stanford University
    Stanford, United States
    Active

Researchers

  • Principal investigator: Wang, Sophia Ying — Stanford University
  • Study coordinator: Wang, Sophia Ying

Related research

Other NIH-funded projects on the same topics.

  • IOP and CSF Pressure in Glaucoma Risk

    This grant studies how eye pressure and cerebrospinal fluid pressure together influence glaucoma risk and vision loss.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11644421

  • Comparing tube positions in glaucoma implants to protect corneal cells

    This trial compares two tube placements for glaucoma drainage implants to see which better protects corneal cells and controls eye pressure in people with uncontrolled glaucoma.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11520347

  • Automated topographic test for glaucoma detection and progression

    A new automated method uses topographic structure-function mapping to help diagnose glaucoma earlier and track its progression in patients.

    NIH research Columbia University Health Sciences · New York, United States · NIH-11516608

  • Using AI on eye scans and genes to predict glaucoma risk

    This project uses artificial intelligence on eye scans, vision tests, and genetic information to find people most likely to develop or have worsening glaucoma.

    NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11469603

  • AI-based glaucoma screening in community health centers

    A new, easy-to-use AI screening approach will be tested in federally funded health centers to help identify people at risk for glaucoma, especially in communities with higher risk.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11454104

  • Understanding how glaucoma genes control eye cell function

    A long-term research project will study how genetic factors affect eye cells in adults with glaucoma to uncover new ideas for protecting vision.

    NIH research Massachusetts Eye and Ear Infirmary · Boston, United States · NIH-11450761

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.