Improving Early Sepsis Prediction with Human-AI Collaboration
Official title: SCH: Improving Early Prediction and Decision-Making for Sepsis with Human-AI Collaboration
Funded at Ohio State University · NIH-11333046 · Data updated 2026-11-12
A patient-focused project aims to help doctors predict sepsis earlier using an AI system that collaborates with clinicians.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | July 17, 2024 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $300,000 |
| NIH project number | 5R01AI188576-03 |
| Project ID | NIH-11333046 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are adults with acute illness who may be at risk for sepsis and are treated in emergency departments or hospital wards.
✕Less likely to help
Patients without acute illness or those not at risk for sepsis may not benefit from this tool.
What this research studies
This project will build an AI tool that uses deidentified patient records to identify sepsis risk earlier in emergency and hospital ward settings. It will include models that quantify uncertainty and offer explanations, so doctors can trust and act on the predictions. The system is designed to fit into clinicians’ workflow and provide actionable insights rather than just a risk score. The work takes place at Ohio State University and involves collaboration between AI researchers and healthcare professionals to improve timely decision-making.
Why it matters
Potential benefit: If successful, it could lead to earlier diagnosis and treatment of sepsis, potentially improving survival and outcomes for patients.
How similar studies have gone: Prior work shows AI tools can aid sepsis prediction, but challenges remain in generalizability and explainability; this study emphasizes human-centered design and uncertainty.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Zhang, Ping — Ohio State University
- Study coordinator: Zhang, Ping
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.