Improving early prediction and decision-making for sepsis using AI and human collaboration

SCH: Improving Early Prediction and Decision-Making for Sepsis with Human-AI Collaboration

NIH-funded research Ohio State University · NIH-11140392

This study is working on a smart computer system that helps doctors spot the early signs of sepsis, a serious condition, by using patient health records to make better predictions and decisions, ultimately aiming to improve care for those at risk.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project IDNIH-11140392 on NIH RePORTER

What this research studies

This research focuses on enhancing the early prediction and decision-making processes for sepsis, a life-threatening condition, by developing a Human-Centered Artificial Intelligence (HCAI) system. The approach involves creating a comprehensive database of patient Electronic Health Records (EHRs) to train machine learning models that can predict sepsis risk more accurately. The system aims to provide actionable insights to physicians, allowing them to make informed decisions in high-pressure situations. By incorporating uncertainty quantification and interactive exploration, the research seeks to improve clinical outcomes for patients at risk of sepsis.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients presenting with symptoms indicative of sepsis in emergency departments or hospital wards.

Not a fit: Patients who are not at risk for sepsis or those who are already in critical care settings may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly increase the chances of early sepsis diagnosis, potentially improving survival rates for affected patients.

How similar studies have performed: Previous research has shown promise in using AI for clinical decision-making, but this specific approach of integrating human collaboration with AI in emergency settings is relatively novel.

Where this research is happening

Columbus, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acute Diseaseacute disease/disorderacute disorderacute kidney injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.