Improving diagnosis and care for rare disorders using advanced technology

Increasing Diversity, Diagnostic Yield, and Efficiency in Clinical Evaluations of Rare Disorders

NIH-funded research University of Alabama at Birmingham · NIH-10979683

This study is looking to improve how we diagnose rare, chronic diseases by using advanced technology, and it's for patients who have been referred by their doctors to get better answers about their health and access to care.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham NIH-funded
Lab location1 site (Birmingham, United States)
Project IDNIH-10979683 on NIH RePORTER

What this research studies

This research focuses on enhancing the diagnostic process for individuals with rare, chronic diseases by utilizing advanced artificial intelligence methods. The University of Alabama at Birmingham's Undiagnosed Diseases Program will evaluate patients referred by their physicians, collecting and analyzing their medical histories and test results. Patients will have the opportunity to participate in evaluations that may include telemedicine appointments and consultations with specialists, aiming to provide clearer diagnoses and better care options. The program is designed to serve diverse populations, particularly those who have historically faced barriers to receiving modern diagnostic services.

Who could benefit from this research

Good fit: Ideal candidates include children and adults with chronic, undiagnosed diseases who have not found answers through traditional diagnostic methods.

Not a fit: Patients with well-defined diagnoses or those whose conditions are not classified as rare may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and timely diagnoses for patients with rare disorders, improving their overall health outcomes.

How similar studies have performed: Previous research has shown promise in using AI for diagnostic purposes, indicating that this approach could lead to significant advancements in the field.

Where this research is happening

Birmingham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.