Improving detection of endometriosis using advanced imaging techniques
Official title: Imaging the Uterotubal Junction for Endometriosis Detection
Funded at University of Arizona · NIH-11177593 · Data updated 2026-11-12
This study is looking at a new, gentle way to see inside the reproductive system to help diagnose endometriosis, a condition that can cause pain and trouble getting pregnant, by using a tiny camera to look at a specific area in women’s bodies without needing surgery.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project start | June 3, 2024 |
| Project end | June 2, 2028 |
| Funding year | 2025 |
| Award (this year) | $42,171 |
| NIH project number | 5F30HD115314-02 |
| Project ID | NIH-11177593 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women of reproductive age who are experiencing symptoms suggestive of endometriosis, such as chronic pelvic pain or infertility.
✕Less likely to help
Patients who do not have symptoms of endometriosis or those who have already been diagnosed and treated may not benefit from this research.
What this research studies
This research focuses on developing a minimally invasive imaging method to accurately diagnose endometriosis, a condition affecting many women and often leading to chronic pain and infertility. The study will investigate the uterotubal junction, a key area in the reproductive system, using a technique called optical coherence tomography (OCT) to visualize structural differences in women with and without endometriosis. By creating a miniature endoscope to access this area, the research aims to provide clearer insights into the condition without the need for invasive surgery.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of endometriosis, improving treatment options and outcomes for affected patients.
How similar studies have gone: Previous research has shown promise in using optical coherence tomography for tissue imaging, indicating potential success for this novel approach in diagnosing endometriosis.
Where this research is happening
-
University of Arizona
Tucson, United States Active
Researchers
- Principal investigator: Long, Dilara — University of Arizona
- Study coordinator: Long, Dilara
Related research
Other NIH-funded projects on the same topics.
-
Molecular clues to endometriosis-related infertility
This grant explores how molecular changes in endometriosis contribute to infertility, with the aim of finding better ways to diagnose and treat the condition.
-
Hormonal Influences on Inflammation in Endometriosis
A study in adult women with endometriosis looks at how hormones and immune pathways interact to influence inflammation and symptoms.
-
How genes influence endometriosis in women of different racial and ethnic backgrounds
The team will compare genetic changes in tissue from women of various races who have endometriosis to find molecular targets for better treatments.
-
Quantum diamond sensor endoscopy to map iron in endometriosis
A tiny quantum sensor built into an endoscope will map iron in endometriosis lesions to help diagnose the disease noninvasively.
-
Understanding how RPLP1 affects endometriosis and adenomyosis
A patient-focused look at how a ribosomal protein called RPLP1 may drive tissue changes in endometriosis and adenomyosis and what this could mean for future therapies.
-
CXCR4 methylation in endometriosis and its role as an early biomarker and non-hormonal therapy target
This project explores how changes in CXCR4 gene regulation may help diagnose endometriosis earlier and point toward non-hormonal treatments for the condition.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.