Improving blood vessel growth using engineered cell therapies
Official title: Optimizing Therapeutic Revascularization by Endothelial Cell_Transplantation
Funded at Yale University · NIH-11137351 · Data updated 2026-11-12
This study is looking at new ways to help heal and grow blood vessels using special materials that can slowly release helpful proteins and genes, which could lead to better treatments for patients needing improved blood flow and recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | December 1, 2024 |
| Project end | March 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $36,814 |
| NIH project number | 3R01HL169238-01A1S1 |
| Project ID | NIH-11137351 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with conditions that impair blood vessel growth or require enhanced tissue regeneration.
✕Less likely to help
Patients with stable blood flow and no need for enhanced vascularization may not benefit from this research.
What this research studies
This research focuses on developing advanced materials for delivering proteins and genetic material to enhance the growth of blood vessels. By utilizing 3D bioprinting techniques, the team aims to create microparticles that can release vascular growth factors in a controlled manner, promoting better healing and tissue regeneration. Patients may benefit from improved therapies that enhance blood flow and recovery in various medical conditions. The study will explore new materials that can provide sustained release of these therapeutic agents over time.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for conditions requiring improved blood vessel formation and tissue healing.
How similar studies have gone: Previous research has shown promise in using similar bioprinting and drug delivery approaches for tissue engineering and regenerative medicine.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Pober, Jordan S — Yale University
- Study coordinator: Pober, Jordan S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.