NIH-funded research R01 grant

Image-based tools to spot post-cesarean wound infections across different populations

Official title: Image-based algorithms for remote cesarean surgical site infection diagnoses in diverse populations

Funded at Univ of North Carolina Chapel Hill · NIH-11478410 · Data updated 2026-11-12

Aims to test two image-based computer algorithms to detect infections after cesarean birth, using real patient images from diverse sites to help earlier care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startAugust 15, 2024
Project endMay 31, 2029
Funding year2026
Award (this year)$116,368
NIH project number3R01HD112403-03S2
Project IDNIH-11478410 on NIH RePORTER

Who could benefit from this research

Could help

Women who have recently had a cesarean delivery in participating sites (Rwanda, Ghana, Mexico) and who can provide wound images and follow-up data.

Less likely to help

Patients whose wounds do not show signs of infection or whose data cannot be appropriately captured may not benefit.

What this research studies

This project will validate and update two existing algorithms that analyze wound photos and thermal images to detect surgical site infections after cesarean deliveries. It plans to enroll 6,000 women across Rwanda, Ghana, and Mexico, collecting wound images and infection diagnoses around postoperative day 10. By examining how well the visible and thermal image tools work in diverse skin tones and real-world settings, the study seeks to improve remote monitoring through community health programs. The goal is to determine if these AI tools can generalize beyond their original rural Rwanda data to help clinicians and caregivers identify infections sooner.

Why it matters

Potential benefit: If successful, the tools could enable timely, remote detection of cesarean wound infections, potentially reducing complications and improving recovery.

How similar studies have gone: Previous algorithms showed strong performance in initial sites, with varying sensitivity/specificity, and this study tests broader generalizability.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Hedt-Gauthier, Bethany — Univ of North Carolina Chapel Hill
  • Study coordinator: Hedt-Gauthier, Bethany

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.