Identifying immune responses to pneumonia-causing bacteria
Official title: IDENTIFICATION AND CHARACTERIZATION OF T CELL EPITOPES FROM BACTERIAL PATHOGENS CAUSING PNEUMONIA
Funded at La Jolla Institute for Immunology · NIH-11203615 · Data updated 2026-11-12
This study is looking at how our immune system, especially T cells, responds to bacteria that can cause pneumonia, and it's for people who have pneumonia as well as those who haven't been sick but might have been exposed to these germs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | La Jolla Institute for Immunology NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | September 30, 2024 |
| Project end | September 29, 2025 |
| Funding year | 2024 |
| Award (this year) | $1,123,365 |
| NIH project number | 75N93024C00057-0-9999-1 |
| Project ID | NIH-11203615 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults who have been diagnosed with community-acquired pneumonia or those who are likely exposed to these pathogens.
✕Less likely to help
Patients with pneumonia caused by non-bacterial pathogens or those who are not part of the targeted age group may not benefit from this research.
What this research studies
This research focuses on identifying and characterizing T cell epitopes from bacteria that cause pneumonia, particularly those transmitted in the community. By using bioinformatics, the researchers will identify peptide candidates that are synthesized and tested for recognition by T cells. The study will involve both uninfected individuals who may have been exposed to these pathogens and those with confirmed pneumonia diagnoses, allowing for a comprehensive understanding of immune responses. The goal is to better understand how the immune system reacts to these bacterial infections.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and vaccines for pneumonia, enhancing patient outcomes.
How similar studies have gone: Previous research has shown promise in identifying T cell responses to bacterial pathogens, suggesting that this approach could yield valuable insights.
Where this research is happening
-
La Jolla Institute for Immunology
La Jolla, United States Active
Researchers
- Principal investigator: Peters, Bjoern — La Jolla Institute for Immunology
- Study coordinator: Peters, Bjoern
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.