Identifying brain targets to help control tics in Tourette syndrome using deep brain stimulation
Defining Targets for Tic Detection and Suppression in Tourette Syndrome Deep Brain Stimulation
This study is exploring a new way to help people with Tourette syndrome by using a special device that can adjust its treatment based on their tics, aiming to find the best spots in the brain to reduce those tics for those who haven't found relief with other methods.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-10917124 on NIH RePORTER |
What this research studies
This research focuses on improving treatment for Tourette syndrome (TS) by using deep brain stimulation (DBS) to control uncontrollable tics. The study aims to identify specific brain regions that can be targeted to reduce tics in patients who have not responded to other treatments. By utilizing advanced closed-loop DBS systems, the research will monitor brain activity and adjust stimulation in real-time based on the patient's symptoms. This innovative approach seeks to enhance the effectiveness of DBS for individuals with severe TS.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with severe Tourette syndrome who have not found relief from conventional treatments.
Not a fit: Patients with mild Tourette syndrome or those who have responded well to existing treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for patients with Tourette syndrome, significantly improving their quality of life.
How similar studies have performed: Previous research has shown promise in using deep brain stimulation for Tourette syndrome, but this approach aims to refine and enhance the technique with real-time monitoring and adjustments.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Okun, Michael S — University of Florida
- Study coordinator: Okun, Michael S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.